Both ATRA and As 2O 3 could down regulate the TF antigen, its mRNA transcription and membrane PCA of NB4 cells with a time dependent manner, while DNR was shown to increase these parameters.

• A T R A 和 As2 O3 均呈时间依赖的方式下调 N B4 细胞的 P C A、 T F 抗原水平以及 T F m R N A的转录；