Bone mineral content (BMC), bone mineral density (BMD), and bone size are three important surrogate phenotypes for osteopcrosis. A majority of genetic studies on osteoporosis focus on BMD, only a few studies employed bone size as surrogate phenotype.
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释义
骨矿含量(Bonemineral content,BMC)、骨密度(Bone mineral density,BMD)和骨大小(Bone Size)是骨质疏松症研究的三个重要替代表型,大量的遗传学研究都集中在寻找与BMC和BMD变异相关的基因,然而鉴定与骨大小变异相关基因的研究却很少。