Bioinformatics were applied for analyzing recombination patterns and gene mutations of the IgHV genes. Softwares SYFPEITHI and BIMAS were used for predicting the T cell epitopes in the immunoglobulin heavy chain variable regions.

• 利用互联网生物信息资源分析B ALLIgHV基因的重排类型和基因变异 ,利用SYFPEITHI和BIMAS软件预测IgHV基因编码蛋白质的T细胞表位。