Benzylisoquinoline compounds antagonized calmodulin ( CaM ) to inhibit the activity of CaM-dependent cyclic nucleotide phosphodiesterase ( CaM-PDE ) .

• 苄基异喹啉类化合物拮抗钙调素(CaM),对环核苷酸磷酸二酯酶(CaM-PDE)产生抑制作用。