Beneficial effects of MNS and RZAS on the recovery of coma caused by midbrain injury were observed.The bilateral median nerve stimulation should be applied in the case of treatment with MNS.

• 结论毁损大鼠中脑的被盖部可以造成大鼠的意识障碍模型，MNS或RZAS对大鼠中脑损伤后昏迷具有促醒作用。