Based on the significant difference of solvency between polysialic acid and irreversibly denatured protein, two processes removing protein from the polysialic acid broth were carried out.

• 应用不可逆变性后的蛋白溶解力与聚唾液酸溶解力的显著差异来脱除聚唾液酸发酵液中蛋白质。