Based on the Fick principle and lots of experiments mathematical models were deviaed for quantifying cerebral flow (DBF) and regional cerebral blood flow (rCBF) by SPECT and perfusion agent 99m Tc-ECD.

• 在大量实验的基础上,根据Fick原理,设计了适合用SPECT和脑灌注显像剂~99mTc-ECD定量测定全脑血流量(CBF)和局部脑血流量(rCBF)的两种数学模型。