BackgroundThe GMC proliferation plays an important role in glomerular sclerosis by influencing the ECMs secretion and mechanical injury on the glomerular capillaries.

• 肾小球系膜细胞(GMC)的增殖通过影响细胞外基质(ECM)的分泌和对肾小球毛细血管的机械损伤而在肾小球硬化过程中发挥着重要作用。