BackgroundHereditary spastic paraplegia (HSP or SPG) is a kind of hereditary disorder of nervous system. Autosomal dominant (AD), autosomal recessive (AR), X-linked inheritance have been described for HSP.

• 遗传性痉挛性截瘫(hereditary spastic paraplegia，HSP或SPG)是一种神经系统遗传病，呈常染色体显性遗传(autosomal dominant，AD)、常染色体隐性遗传(autosomal recessive，AR)和X-连锁隐性遗传(X-linked recessive，XR)，其中以AD遗传最为常见。