Background &Objective:5-Fluorouracil(5-FU),a widely used chemotherapeutic dru g,has a limited overall effect in the treatment of human soli d tumors due to resistance.

• 背景与目的:5-FU是临床上重要的化疗药物,但总体疗效有限,如何提高其抗癌疗效一直是临床上亟待解决的难题。