BACKGROUND & OBJECTIVE: Bcl-2/ElB 19kDa interacting protein3-like (BNIP3L) gene is a tumor suppressor gene cloned from a human fetal liver cDNA library, locating at 8p21, one of the high frequent LOH regions in lung carcinoma.

• 背景与目的：BCl-2/ElB 19 kDa-interacting protein 3-like (BNIP3L)基因是从人胎肝cDNA文库中克隆得到的具有抑瘤活性的新基因，定位于8p21肺癌高频杂合性丢失(loss of heterozygosity，LOH)区；