BACKGROUND & OBJECTIVE: Adenosine diphosphate ribosyltransferase (ADPRT) and X-ray repair cross-complementing 1 (XRCC1) are 2major DNA base excision repair (BER) proteins and act interactively instimulating and executing BER processes.

• 背景与目的:DNA修复缺陷是肿瘤的遗传易感因素。 二磷酸腺苷核糖转移酶(adenosinediphosphateribosyltransferase,ADPRT)和X线修复交叉互补蛋白1(X-rayrepaircross-complementing1,XRCC1)是碱基切除修复的重要成分。