Aspc-1 and Bxpc-3 can be improved by increment of the local drug concentration and prolongation of the exposed time by intraarterial infusion or consecutive arterial infusion through the reserved catheter.

• 胰腺癌细胞株Aspc一1和BxPc一3的生长抑制率随着药物浓度的增加和作用时间的延长而显著上升，通过动脉灌注或保留导管持续灌注以提高化疗药物局部浓度及延长药物作用时间能够改善胰腺癌的化疗效果。