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- METHODS One hundred samples of breast cancer specimens were analyzed by SABC immunohistochemical staining for anti apoptotic gene bag 1 expression. 方法 采用免疫组化SABC法观察了 10 0例乳腺癌与 10例乳腺良性肿瘤及 10例正常乳腺组织的石蜡标本切片中 bag- 1的表达 .
- Crook N E, Clem R J, Miller L K, 1993. An apoptotic genes of baculovirus gene with a zinc finger-like motif. J. Virol., 67:2 168- 2 174. [贡成良,小林淳,宫岛成寿等,1999美国白蛾核型多角体病毒几丁质酶基因核苷酸序列研究病毒学报,15(3):260-269
- Compared to COC_1. 143 genes were differentially expressed significantly in COC_1/DDP cells, among which 12 ribosomal protein genes were down-regulated significantly, many anti-apoptotic genes were up-regulated and apoptotic gene CASP2 was down-regulated. 在143个表达水平发生改变的基因中,有12个核糖体蛋白基因表达下调,多个凋亡抑制基因表达上调,凋亡诱导基因CASP2表达下调。
- Thechangesof apoptosisThe expression of bd-2 was not found in the apoptotic genes, and the least in theneurons of models, which reveals the dues of the relationship between the apoptosls ofageing neurons and the regulation of the expression of gene. D-半乳糖模型组神经元TUNEL阳性率最高，提示其脑神经细胞数目减少，细胞脱失有细胞凋亡机制参与； 同时模型组抗凋亡基因Bcl-2mRNA表达最少，为揭示衰老细胞凋亡与基因表达调控之间的关系提供线索。
- apoptotic gene prorein expression 凋亡基因蛋白表达
- Results Among 96 apoptotic genes , we found that the expression of 23 genes [Survivin; Bcl-2; TNF-b/Lta; TNFa , etc] was up-regulation, while the expression of 22 genes [Bak; Bax; Bik; P53 , etc] was down-regulation in laryngeal cancer . Bak、Bax、Bik、P53等22个基因表达下调。 结论 通过细胞凋亡GEArray Q芯片膜杂交筛查的方法发现,在喉鳞癌中抑制凋亡的基因表达上调,促进凋亡的基因表达下调,这些基因改变组成了喉鳞癌特异的与凋亡相关的基因表达谱,为全面系统地研究喉鳞癌中与凋亡相关基因表达情况,及探讨喉鳞癌的发病机制提供了有益的线索。
- Keywords Hepatocarcinoma model;Apoptotic gene;Immunodeficient mice; 关键词肝癌模型;凋亡基因;免疫缺陷小鼠;
- Keywords human hepatocarcinoma model;apoptotic gene;imm unodeficient mice; 关键词肝癌模型;凋亡基因;免疫缺陷小鼠;
- Keywords minipigs;DM animal model;gastricelectrical activity;Piweikang;apoptotic gene; 小型猪;糖尿病模型;胃电;“脾胃康”;凋亡基因;
- Keywords Leukopenia;DiGan Oral Liquid;Traditional Chinese medicine treatment;Adhesion molecule of mice;White cell antigen;Apoptotic gene cell cyclin; 白细胞减少症;地甘口服液;中医药疗法;小鼠;粘附分子;白细胞抗原;凋亡基因;细胞周期素;
- TNC are able to digest and clear apoptotic TNC-T. TNC能消化和清除凋亡的TNC T。
- At the arrow is a rounded pink apoptotic body. 箭头示粉红色的凋亡小体。
- Bcl - 2 usually act against apoptotic cell death. 有时新生儿和2岁以内婴幼儿的腹泻和胃肠炎是由致病性E.
- FCM was used to assay the change of apoptotic rate. 应用流式细胞仪检测细胞凋亡率的变化；
- The position that a given gene occupies on a chromosome. 基因座在一条染色体上某种给定基因所占的位置
- Half of the people who inherit the gene express it. 半数有这种遗传基因的人，皆显示出其影响
- Now the variant of each gene is called an allele. 每一种基因的变化就叫做等位基因。
- We know a lot about the structure of gene now. 如今我们对基因的结构有了较多的了解。
- A single gene may have many effects. 单一基因可能具有很多种效应。
- There can be more than two alleles for a gene. 一个基因可能有两个以上的等位基因。
