Aplasia cutis congenita (ACC) is a rare developmental malformation characterized by the absence of skin, and often extends to bone or dura in a localized or widespread area at birth.

• 摘要先天性皮肤发育不良症是一种罕见的先天性发育异常，临床上可见在出生时，有局限性或广泛性的皮肤缺损，且常常深达骨组织或是软脑膜。