Animals were sacrificed at months 0.5,1,2,3,5,7 and 9 in the non-induced group and at months 1,2,3,4,5 and 7 in the induced group after operation. Defect repair and type of new tissues were observed.

• 术后未诱导组于0.；5；1；2；3；5；7；9个月；诱导组于1；2；3；4；5；7个月分别处死动物；观察缺损修复情况及新生组织类型。