And in vivo experiment,the antibacterial effect of each acidifier formulation and multielement regression equation between the antibacterial effect and the percentage of each acids in acidifier formulation were obtained.

• 利用磷酸、甲酸、柠檬酸、乳酸等4种酸,用均匀设计的方法组成20种酸化剂配方,以体外抑菌试验研究各个酸化剂配方的抑菌效果并建立各酸在配方中的百分比与抑菌率的多元回归方程,优化求解得最佳抑菌效果酸化剂配方。