Anaphylaxis is usually mediated by an immunologic mechanism involving immunoglobulin E and resulting in sudden systemic release of mast-cell and basophil mediators including histamine and tryptase.

• 速发型过敏反应通常是由包括免疫球蛋白E（IgE）在内的免疫机制介导，导致组织突然释放肥大细胞、嗜碱性细胞分泌的介质，包括组胺、类胰蛋白酶。