Among theses targeting moieties, disulfide-stabilized Fv or Fab fragment has disulfide bond to conjoin the heavy chain and the light chain to increase the stablility, but it is difficult to express in host or has a poor yield.

• 在单链抗体、二硫键抗体、Fab抗体这几种导向载体中,二硫键抗体、Fab抗体因重链和轻链之间有二硫键相连,稳定性较高,但表达困难或较难获得较高产量;