Among high risk type in over 100 HPV genotypes, HPV16 plays a major role in the pathogenesis of condyloma acumilatum(CA), cervical cancer and cervical intraepithelial neoplasia.

• 现已知HPV有100余种亚型，其中高危型HPV16可导致尖锐湿疣、宫颈上皮内瘤和宫颈癌等疾病。