Aminoglycoside modifying enzyme is the main resistance mechanism.In this review,some advances in the research of aminoglycoside modifying enzyme inhibitor are summarized.

• 氨基糖苷类抗生素的修饰酶是细菌耐药的主要机制,本文对氨糖类抗生素的修饰酶抑制剂的研究进展作一综述。