Although inactivation of some tumor suppressor genes such as p53 and p16INK4A has been identified, no known oncogene is commonly activated in hepatocellular carcinomas.

• 肝癌是亚洲及非洲最常见的恶性肿瘤，其原因可能是由于这些地区肝炎病毒的流行以及经常接触肝癌的特异性致癌物质。