All strains of non tuberculosis mycobacteria were shown with highly tolerance to PAS,and high to SM,INH,RFP,EBM and less(sensitive)to KM,TH.

• 非结核分支杆菌对PAS呈高度的耐药性，对SM、INH、RFP、EBM等耐药性也较高，对KM、TH较敏感。