Aim To observe the effects of insulin like growth factor 1(IGF 1) on neuronal loss in the cerebral cortex following diffuse brain injuries(DBI) in rats and investigate the possibility of IGF 1 in treating the brain injuries.

• 目的观察胰岛素样生长因子-1(insulin-likegrowthfactor-1,IGF-1)对大鼠弥漫性脑损伤(diffusebraininjury,DBI)皮层神经元死亡的影响,探讨应用IGF-1治疗脑损伤的可行性。