Aim To establish a new and sensitive HPLC-MS met ho d for the determination of zolmitriptan in human plasma and study the pharmacoki netics of zolmitriptan in healthy volunteers.

• 目的建立测定人血浆中佐米曲普坦血药浓度的液质联用方法,研究佐米曲普坦在中国健康志愿者体内药代动力学。