After formation of biofilms,drug resistance of Candida albicans obviously strengthens.It can be nearly resis-tant to all of the antifungal agents except echinocandins and amphotericin B liposomes.

• 白念珠菌形成生物膜后耐药性明显增加,几乎对所有抗真菌药物(除了棘球白素和两性霉素B脂质体)具有高度耐药性。