After beieg exposed respectively to As2O3 ( 45mg/kg/day ) P ( 3mg/kg/day ) and CCl4 ( 990mg/ kg/day ) by oral administration for four days, all three groups of Wistar rate showed remarka ble liver pathological changes.

• 大鼠每日分别经口染毒三氧化二砷(45mg/kg)、黄磷(3mg/kg)、四氯化碳(990mg/kg),连续4日后,均出现肝脏病理改变。