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- Adenovirus mediated p53 gene 重组人p53腺病毒
- Adenovirus mediated angiostatin gene therapy for rat glioma. 重组腺病毒载体介导血管抑素基因治疗大鼠脑胶质瘤的实验研究。
- Adenovirus CNHK600-p53 carrying p53 gene can enhance chemosensitivity of BEL7404 hepatocarcinoma cell line. Gene therapy using adenovirus CNHK600-p53 in combination with chemotherapy may be a new strategy for hepatocarcinoma treatment. 携带p53基因的CNHK600-p53能提高肝癌细胞株BEL-7404对化疗药物的敏感性,CNHK600-p53联合化疗药物治疗可望开辟克服肝癌耐药的新途径。
- P53 gene is localized in the short arm of human chromosome 17. P53基因定位于人类第17号染色体的短臂，野生型P53基因是肿瘤抑制基因。
- The scientists measured mutations in the P53 gene,the most frequently mutated gene in human cancer. 科学家们对P53基因的突变体进行了测量，该基因是人类患癌症时最经常发生突变的基因。
- Adenovirus mediated hIL-2 gene transfer to bladder epithelium in vivo 腺病毒介导hIL-2基因转染膀胱上皮的体内研究
- The scientists measured mutations in the p53 gene, the most frequently mutated gene in human cancer. 科 学 家 们 对 P53基 因 的 突 变 体 进 行 了 测 量 ， 该 基 因 是 人 类 患 癌 症 时 最 经 常 发 生 突 变 的 基 因 。
- The results of PCR-SSCP analysis showed that 2 out of 4 SPA with abnormal exon 8 of p53 gene. PCR-SSCP分析显示,本研究的4例涎腺多形性腺瘤组织中,2例出现第8外显子异常电泳带; 1例出现第6外显子异常条带。
- Conclusbo: It suggsts that ras gene aed p53 gene mutation may be related with L- form infedtbo. 结合提示L型感染参与了ras原癌基因激活和p53抑癌基因的失活。
- AIM:To explore gene mutations of p53 gene in samples of keloid pedigrees and the relation of keloid onset. 目的:探讨瘢痕疙瘩家系样本有无p53基因突变以及与瘢痕疙瘩发病的关系。 方法:实验标本来自南方医科大学南方医院整形外科2005年收集的A和B两个瘢痕疙瘩家系。
- Methods :P53 gene mutation patterns in 20 cases of HCC by polymerase chain reaction (PCR) and PCR prod-ucts sequencing. 方法:应用多聚酶链式反应(PCR)结合PCR产物测序,同时检测肝癌P53蛋白表达。
- Gene mutations in p53 gene exon 11 were identified in all samples,which had the same type and site. p53基因外显子11在所有的被检测样本中均发现突变,而且突变的位点及突变的类型均相同。
- The high mutation rate of p53 gene may indicate that PSH has potentially malignant biological behavior. p53基因的高突变率提示PSH可能具有潜在的恶性生物学行为。
- Mutations in P53 gene or interactions of wild-type p53 protein with E6 protein synthesized by HPV may result in SCCL. P53基因突变或野生型P53蛋白与HPV合成的E6蛋白结合可能会导致肺鳞癌的发生。
- Recombinant adenovirus mediated HSV-TK gene in vessel-targeted treatment of subcutaneously implanted HHC in mice 腺病毒介导HSV-TK基因血管靶向治疗裸鼠皮下人肝癌细胞移植瘤
- Adenovirus mediated double suicide gene selectively kills human umbilical vein endothelial cells 腺病毒介导双自杀基因选择性杀伤血管内皮细胞
- A comparative study on p53 gene mutation in primary human Dukes C col on cancer with that in matched lymph node metastasis. Dukes C期大肠癌原发灶与淋巴结转移灶中p53基因突变的比较
- Study on Anti-Glioma Effect of Recombinant Adenovirus Mediated HSV-TK/ACV System Enhanced by wt-p53 Gene in vitro p53基因增强恶性胶质瘤HSV-TK/ACV系统疗效的体外研究
- Objective To ascertain the feasibility of detecting p53 gene mutations for early diagnosis of lung cancer using spu-tum from postbronchoscopy. 目的 探讨纤支镜后痰液标本的p53基因突变检测用于肺癌早期诊断的可行性。
- Experimental Study on Gene Therapy of Human Epidermal Carcinoma by Recombinant Adenovirus Mediated AntisenseMMP-2cDNA 重组腺病毒介导的反义MMP-2cDNA基因治疗人表皮癌的实验研究
