Acute oral toxicity on mouse and acute dermal toxicity experimentation on rabbits indicated that B25W-antibiotic was innoxious.

• 通过单因子和均匀设计实验，优化菌株B25W摇瓶发酵条件。 确定最佳发酵培养基：玉米粉0.；34%25，豆饼粉1