Abatacept is used in combination with methotrexate, when other disease modifiying antirheumatic drugs (DMARDs, eg sulfasalazine, infliximab) have not been effective or are not tolerated.

• 当其他的抗风湿药（抗风湿药，乙二醇柳氮磺胺吡啶，英夫利昔单抗）无效或者难以忍受时，调节剂如阿巴西普和氨甲叶酸结合用于治疗