AIM:To observe the effects of P.gingivalis and P.intermedia LPS on the production of IL-6 and IL-8 from human gingival fibroblast cells and the effect of LPS on hGFs was mediated by mCD 14 or not.

• 目的 :观察牙龈卟啉菌和中间普氏菌LPS刺激人牙龈成纤维细胞合成IL - 6、IL - 8的能力 ,并了解LPS是否通过细胞表面膜受体mCD14 介导信号传导。