AIM: To construct the recombinant adenoviral vector carrying antisense RNA to chemokine receptors CCR5 and CXCR4 and to obtain recombinant adenovirus, which will be used to resist HIV 1 infection.

• 目的 :构建趋化因子受体CCR5 ；CXCR4双靶区反义RNA重组载体并获取重组腺病毒以用于抗HIV 1基因治疗的研究 .