AIM To study drug resistance mechanism of gastrointestinal tumor, we developed MKN28/VCR, MKN45/VCR which were vincristine-resistant cell lines of human gastric cancer.

• 目的为研究消化道肿瘤的耐药机制,建立了2株体外人胃腺癌长春新碱耐药细胞系MKN28/VCR和MKN45/VCR。