AES(amino-terminal enhancer of split), also named GAM(gpl30 associated molecule), had been proved to be associated with gp! 30 at its cytoplasmic membrane proximal part, and co-expression of AES. gp!

• AES(amino-terminal enhancer of split)分子又名gP130结合分子(Sp130 associated molecule，GAM)，由197个氨基酸残基组成，能与gp130分子胞浆区近膜段结合。