ABP-CM4 strongly bound to E. coli LPS, as proven by the limulus amoebocyte lysate (LAL) assay.Effects of LPS on the bactericidal action of the peptide were assessed.

• 通过抗菌肽首先和革兰氏阴性菌外膜上的脂多糖相互作用从而破坏细菌外膜这个作用机理，我们首次探讨了抗菌肽CM4具有中和内毒素的作用。