A single nucleotide polymorphism (SNP) in the PTPN22 gene known as +1858C>T was recently reported to be associated with several autoimmune diseases including autoimmune thyroid disease (AITD).

• 最近报道该基因的+1858C>T单核苷酸多态性（SNP）与多种自身免疫性疾病相关，其中包括自身免疫性甲状腺病（AITD）。