A method was established for determining two intermediates in synthesis of imidacloprid,2 chloro 5 methyl pyridine and 2 chloro 5 chloromethyl pyridine by HPLC.

• 建立了用高效液相色谱法同时测定农药吡虫啉中间体2-氯-5-甲基吡啶和2-氯-5-氯甲基吡啶含量的方法。