A major step in the pathogenesis of atherosclerosis is the vectorial migration of vascular smooth muscle cells (VSMC) from the arterial media through the internal elastic lamina into the intima and their subsequent proliferation in the intima.

• 血管平滑肌细胞(vascular smooth muscle cell,VSMC)由中膜向内膜移行并异常增殖是 As 及再狭窄发病机制中的关键环节。