A linear epitope recognized by c2410, a18, WH303 MAbs which is strongly conserved in CSFV strains but highly divergent among BVDV and BDV strains have been precisely defined and located at ,SPTTLR(aa832-837) of E2 molecule.

• 鉴定获得WH303单克隆抗体识别的2个主要拟位：IfNnrT、AxIFPMTA及单抗M1669识别 3个主要拟位DxW、SLMPP、MLLH，并经ELISA和兔疫印迹检测获得证实，但在病毒EZ蛋白分子的氨基酸序列中未发现相同或相似的氨基酸序列。