A culture medium for Coprinus comatus has been designed whereby the non-enzymatic glycation-inhibiting activity of the fermentation broth was maximized.

• 试验以抑制非酶糖基化反应活性为指标,通过单因素试验筛选了适宜碳源、氮源、无机盐以及复合营养因子,通过正交试验进一步优化培养基组成。