(R,S)-2-Aminopropanol was prepared by acetoxylation of 1-chloropropanone with sodium acetate,followed by alkaline hydrolysis and reductive amination under hydrogen in the presence of Raney Ni with an overall yield of44%.
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释义
氯丙酮经乙酸基化、碱性水解、Raney Ni催化还原胺化得到(R,S)-2-氨基丙醇,总收率44%25。
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